Hard-to-crack ex-CIA man Jack Byrnes and his wife, Dina, travel to the warmer climes of Florida to meet the parents of their son-in-law-to-be, Greg Focker. While Greg and his bride-to-be may be happily matched, the first meeting between the Byrnes family and the Focker family quickly turns into a clash of opposites, as the future in-laws discover that attraction does not always extend to the parents.